CX3CR-1GFP transgenic mice (B6.129P2(Cg)-Cx3cr1tm1Litt/J; Jax stock number: 005582)
The CX3CR-1GFP knock-in/knock-out mice express EGFP in monocytes, dendritic cells, NK cells, and brain microglia under control of the endogenous Cx3cr1 locus. These mice may be useful in studies of leukocyte migration and trafficking, as well as for transplantation studies.
Optimized Retron Editors for Enhanced Genome Engineering in Mammalian Cells
Efficient and scalable method for complex genome editing in mammalian cells that are compatible with lentiviral delivery.
miRNA-Mediated Transgene Expression System for Improved Gene Therapies and Research Reagent Applications
A highly specific and tailorable transgene expression systems compatible with conventional gene therapy platforms
CD11c-DTR Transgenic Mice (B6.FVB-1700016L21RikTg [Itgax-DTR/EGFP] 57Lan/J; Jax stock number: 004509 )
The CD11c-DTR/GFP transgenic line 57 has the CD11c promoter (Itgax) directing expression of a diphtheria toxin receptor - enhanced green fluorescent protein (DTR/GFP) fusion protein to dendritic cell populations. (B6.FVB-1700016L21RikTg [Itgax-DTR/EGFP] 57Lan/J; Jax stock number: 004509 )
TET2 Conditional Knockout Transgenic Mice
Conditionally-inducible mouse model for studying hematopoietic stem cell self-renewal and myeloid transformation. (B6;129S-Tet2tm1.1Iaai/J; Jax stock number: 017573)
Human Immunodeficiency Virus 1 (HIV-1) NL4-3 ΔEnv Vpr Luciferase Reporter Vector (pNL4-3.Luc.R-E-)
The HIV-1 NL4-3 luciferase reporter vector contains defective nef, env, and vpr genes cloned into pUC19. This reporter vector is useful for studying the role of the Nef and Vpr proteins in HIV infections and pathogenesis.
Nano Zeolite-Y: A Novel and Cost-Effective Antibacterial Composition
A novel and cost-effective inorganic antibacterial composition.
PKP2cKO Transgenic Mouse Model
Conditionally-inducible mouse model for arrhythmogenic right ventricular cardiomyopathy (ARVC), an inherited type of heart disease that can cause sudden death.
Transgenic Mouse Model Expressing C217G Uromodulin
Transgenic mouse model expressing a human uromodulin mutant mimicking hereditary human mutant uromodulin caused kidney diseases for testing diagnostics and therapy.