Murine Cell Line - Kras G12D/Lkb1 -/-
Murine cell line Kras G12D/Lkb1 -/- for studying Kras-driven cancers, such as non-small-cell lung cancer (NSCLC).
Technology No. WON02-08
LKR10 and LKR13 KrasG12D-mutant LUAD cells (on a 129/Sv genetic background, previously generated in the laboratory of T. Jacks) were transiently transfected with Keap1 CRISPR–Cas9 KO plasmid (sc-424513-KO-2) or Stk11/Lkb1 CRISPR–Cas9 KO plasmid (sc-423192).