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KaryoCreate: Generating Chromosome-Specific Aneuploidies in Human Cells

Chromosome-specific aneuploidies on the cellular level.

Personalized Ex Vivo Platform for Testing Patient Responsiveness to Therapeutics for Inflammatory Disorders

A novel and innovative organoid co-culture system for studying immune-mediated tissue damage and testing patient responses to therapies for inflammatory disorders.

Rapid Generation of Single-Chain Antibodies for Use as Chimeric Antigen Receptors (CARs)

Rapid and efficient identification of high-affinity, antigen-specific single-chain antibodies for the construction of chimeric antigen receptors (CARs) to improve the effectiveness of CAR T-cell therapies, particularly in targeting challenging cancer antigens.

iCADD: Next-generation Screening Platform for Identifying Small Molecular Glue Degraders

An efficient, high-throughput platform to rapidly identify protein degraders targeting undruggable proteins for therapeutic development.

Innovative Clasping Antibody Platform for Producing High-Performance Antibodies to Challenging Targets

An innovative platform for generating antibodies with high affinity, high specificity, and low lot-to-lot variability against challenging target antigens.

In Silico, Machine Learning-Based Platform to Identify Disease-Causing Senescent Cells

Accurate and reproducible method to identify senescent cells for diagnostic and therapeutic applications.

Optimized Retron Editors for Enhanced Genome Engineering in Mammalian Cells

Efficient and scalable method for complex genome editing in mammalian cells that are compatible with lentiviral delivery.

Sindbis Virus-Based Vectors for the Oncolytic Immunotherapy of Solid Tumors

Innovative, efficacious, and safe treatment for ovarian and other types of cancers.

SCRATCH-seq: Capturing Dynamic Genetic Changes in Lymphocytes

A platform that allows the combined profiling of chromatin accessibility, transcription analysis with parallel analysis of B and T lymphocytes antigen repertoire.

miRNA-Mediated Transgene Expression System for Improved Gene Therapies and Research Reagent Applications

A highly specific and tailorable transgene expression systems compatible with conventional gene therapy platforms

Chip-based Prognostic Tool for Improved Leukemia Treatment Outcomes

Accurate, inexpensive, and rapid predictive tool to assess patient responsiveness to immunotherapies, such as chimeric antigen receptor (CAR) T-cell therapy

PHOTACS: Photo-Activatable PROTACS

Spatial and temporal control over protein target degradation in diseased tissue

Photoactivatable Lipid Nanoparticles for Drug Delivery

Novel photoactivatable lipid nanoparticles for drug delivery that allow for light-triggered drug release at the disease site

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