Optimized Retron Editors for Enhanced Genome Engineering in Mammalian Cells
Efficient and scalable method for complex genome editing in mammalian cells that are compatible with lentiviral delivery.
Sindbis Virus-Based Vectors for the Oncolytic Immunotherapy of Solid Tumors
Innovative, efficacious, and safe treatment for ovarian and other types of cancers.
SCRATCH-seq: Capturing Dynamic Genetic Changes in Lymphocytes
A platform that allows the combined profiling of chromatin accessibility, transcription analysis with parallel analysis of B and T lymphocytes antigen repertoire.
miRNA-Mediated Transgene Expression System for Improved Gene Therapies and Research Reagent Applications
A highly specific and tailorable transgene expression systems compatible with conventional gene therapy platforms
Chip-based Prognostic Tool for Improved Leukemia Treatment Outcomes
Accurate, inexpensive, and rapid predictive tool to assess patient responsiveness to immunotherapies, such as chimeric antigen receptor (CAR) T-cell therapy
PHOTACS: Photo-Activatable PROTACS
Spatial and temporal control over protein target degradation in diseased tissue
Photoactivatable Lipid Nanoparticles for Drug Delivery
Novel photoactivatable lipid nanoparticles for drug delivery that allow for light-triggered drug release at the disease site