Mutant-Selective HER2 Antibodies for Treatment of Major Cancer Types
Selective, differentiated, and efficacious antibody-based treatment for mutant HER2-mediated cancers without HER2 overexpression.
Sindbis Virus-Based Vectors for the Oncolytic Immunotherapy of Solid Tumors
Innovative, efficacious, and safe treatment for ovarian and other types of cancers.
Monoclonal Antibodies for Efficient Removal of Uremic Toxins in Chronic Kidney Disease Patients
Effective removal of pathological albumin-bound uremic toxins in Chronic Kidney Disease patients, which are not removed by standard hemodialysis.
Apoptosis Inhibitor 5 (API5)-based Therapeutic for the Treatment of Inflammatory Bowel Diseases
A novel disease-modifying treatment of inflammatory bowel diseases that doesn't compromise the patient immune system.
Selective KRAS(G12D)-Binding Monobodies for the Treatment of Cancer
A selective, efficacious and versatile treatment for KRAS(G12D)-driven cancers
Selective NRAS-Binding Monobodies for the Treatment of Cancer
A selective and efficacious inhibitor of NRAS applicable to all NRAS-driven cancers.
Novel Probiotic Compositions for Improving Metabolism and Immunity
Innovative probiotic formulation to prevent and treat metabolic and immune disorders
Therapeutic Hyaluronic Acid and Peptide Composition for Regenerative Repair of Cartilage Injury
Innovative disease-modifying method to treat knee cartilage injuries and prevent development of post-traumatic osteoarthritis (PTOA)
Injectable Therapeutic Hydrogel for the Treatment of Post-Traumatic Osteoarthritis
Injectable, minimally invasive, and effective disease-modifying therapeutic for post-traumatic osteoarthritis (PTOA) prevention and treatment
Hydrophobically Interspaced, Charged Peptides for the Treatment and Prevention of Dementia
An Innovative and efficacious therapeutic strategy to prevent and/or treat AD and other dementias.
Anti-CD97 Antibody-Drug Conjugates for the Treatment of AML and GBM
Innovative, efficacious, and improved treatment option for Acute Myeloid Leukemia (AML) and Glioblastoma (GBM)
High-Throughput Design and Engineering of Mammalian Cells
A novel approach for designing, building, and delivering large DNA vectors (>100kb) for highly customizable expression of multiple gene products.
Vectored ACE2 Receptor Decoy for Prevention and Treatment of Pan-Coronavirus Infections
Innovative, alternative, and complementary treatment option for pan-coronavirus infections
Targeting the SARS-CoV-2 Viral-Immune Interaction for COVID-19 Therapy
New and innovative therapeutic approaches for blocking SARS-CoV-2 engagement with immune cells
Steroid Modulators of Treg Lymphocytes and Pro-Inflammatory T Helper Cells For Autoimmune Disease
Innovative methods to modulate host T regulatory (Treg) and Th17 cells in autoimmune disease treatment.
Engineered Progranulin: A Promising Therapeutic Approach for Autoimmune Diseases
New efficacious TNFα inhibitors for the treatment of Rheumatoid arthritis and other autoimmune diseases.
Multivalent Steroid Conjugates for Treatment of Castration-Resistant Prostate Cancer (CRPC)
A new generation of therapeutics for treating patients with enzalutamide-resistant CRPC.
Netrin-1 and UNC5B as Novel Targets in Metabolic Liver Diseases: NAFLD & NASH
Innovative and effective therapies for treating Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic SteatoHepatitis (NASH)
FGF23 Ligand Trap: New Biologic for Treating Kidney Diseases
Innovative and efficacious treatments for chronic kidney disease and phosphate-wasting diseases.
Chimeric FGF21: Treatment of NAFLD, NASH and Hepatic Steatosis
New and efficacious versions of fibroblast growth factor 21 (FGF21) for metabolic liver diseases
Angiotensin-Converting Enzyme 2 (ACE2) Immunoadhesin Microbody
Improved therapeutic approaches for blocking SARS-CoV-2 entry into host cells
Novel Lumican-Binding Peptides Acting on the Toll-Like Receptor Pathway in Inflammation and Related Conditions
Novel peptides for treating conditions or diseases resulting from dysregulation in the immune system, such as septic shock, wound healing and autoimmune diseases.